Written in EnglishRead online
Includes bibliographical references and index.
|Statement||edited by Bostjan Kobe, Mitchell Guss, Thomas Huber.|
|Series||Methods in molecular biology -- 426, Methods in molecular biology (Clifton, N.J.) -- 426.|
|Contributions||Kobe, Bostjan., Guss, Mitchell., Huber, Thomas, Dr.|
|LC Classifications||QP551 .S856 2008|
|The Physical Object|
|Pagination||xxvi, 601 p. :|
|Number of Pages||601|
|LC Control Number||2007937390|
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Structural Proteomics: High-Throughput Methods, Second Edition begins by exploring the resources available for curation, annotation, and structure prediction in silico, and continues with methods for sample preparation of both proteins and crystals, as well as structural characterization techniques.
Structural genomics seeks to describe the 3-dimensional structure of every protein encoded by a given genome-based approach allows for a high-throughput method of structure determination by a combination of experimental and Structural proteomics book principal difference between structural genomics and traditional structural prediction is that structural genomics attempts to determine.
The total number of proteins expressed in a cell is called a proteome. This chapter describes the importance of proteomes and proteomics techniques. Different protein isolation methods are analyzed. Important proteomics techniques are discussed. Different branches of proteomics such as structural proteomics, functional proteomics are also.
Bioinformatics methods and applications for functional analysis of mass spectrometry based proteomics data. This book is intended to serve both as a textbook for short bioinformatics courses and as a base for a self teaching endeavor.
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Proteomics for Biological Discovery begins by discussing the emergence of proteomics technologies and summarizing the potential insights to be gained from proteome-level research. The tools of proteomics, from conventional to novel techniques, are thoroughly covered, from underlying concepts to limitations and future directions.
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Written by leading experts in the field, it provides readers with an understanding of new and. Get this from a library. Structural proteomics: high-throughput methods. [Bostjan Kobe; Mitchell Guss; Thomas Huber, Dr.;] -- Annotation The objective of this volume is to provide readers with a current view of all aspects of the 'pipeline' that takes protein targets to.
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Structural and Functional Proteomics Structural proteomics is the determination of atomic resolution 3-dimensional protein structures on a genome-wide scale in order to ascribe biochemical functions to gene products and to better understand the relationship.
This volume is a high-level survey of the newly emerging concepts of structural biology and functional genomics for biologists, biochemists and medical researchers interested in genome research.
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Some of the limitations or bottle-necks in proteomics include large and uncurated databases, low affinity to the separation of peptides, and the many types of post translational modifications of proteins that lead to much more complexity -- not only of Tertiary structure and Quaternary structure, but also actions, effects, and functions of a.